SWACCS Seminar Series:
ONE health perspective, the risks posed by chemicals on ecosystem and human health
When: Wednesday, 19. October 2022, 14:00 - 15:00
Where: Zoom Meeting ID: 628 2913 3221 Passcode: 657526
Speaker: Veronica Lizano-Fallas, PhD student at the Department of Biomedical and Clinical Sciences, Linköping University
Title: “Proteomics as key aid for addressing the 21st century challenge of chemical risk assessment”
Abstract: The development of novel methodology to unbiased identification of mechanisms of action of chemicals, including novel or poor-studied compounds without any previous solid knowledge, or even compounds in a phase of chemical characterization, would address one of today´s challenges of environmental and human toxicology. Traditional methodologies evaluate the impact in well-known pathways that have been previously described as affected by one specific compound. Therefore, there are several assays that are routinely evaluated however will not offer a specific response for one single compound. In our project, we envisioned that the application of thermal proteome profiling approaches combined with multi-criteria decision-making analysis could be a promising alternative to gain time and resources in chemicals assessment.
Speaker: Natàlia Corcoll, Associate Professor at the Department of Biological and Environmental Sciences, University of Gothenburg
Title: “Structural and functional responses of aquatic biofilms under chemical stress: from molecules to communities”
Abstract: The high degree of chemical pollution in aquatic ecosystems and the decrease of biodiversity and community functions have raised the urgent need for ecotoxicological studies using natural communities. In this seminar I will present results from several ecotoxicological studies in Swedish rivers and microcosms experiments using freshwater and marine biofilms, focusing on impacts on algal and microbial diversity, tolerance acquisition, primary production, and biofilm quality (food resource for benthic microorganisms).